TxDOT lists the right lane of southbound US 281 as closed from 1.182 miles south of SH 46 to 533.28 feet south of SH 46 for base-repair paving from Oct. 25 through Oct. 26.
Drivers using that stretch of southbound US 281 can expect delays; TxDOT lists no detour.
From the source record
TxDOT DriveTexas construction recordUS 281 southbound right-lane closure
Right Lane Closed on US 281 SB for Base Repair PavingTexas Department of Transportation, DriveTexas ↗
The work is a short paving repair on the southbound right lane. TxDOT's entry identifies the location by its distance south of SH 46, so drivers approaching that stretch should watch for the lane closure rather than expect a signed alternate route.
The posted end date is Oct. 26. Drivers can check the US 281 entry on DriveTexas, using the location south of SH 46 or the record ID 327573E3-C281-4D31-806A-A4E1A20E1DE9, for the current construction listing.